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1

Environnement périnatal : marques épigénétiques et déterminisme des maladies métaboliques de l’adulte. Preuves de concept

Portha, Bernard, Fournier, Alexandra, Kioon, Marie Dominique, Mezger, Valérie, Movassat, Jamileh

Journal:

Cahiers de Nutrition et de Diététique

Year:

2013

Language:

french

File:

PDF, 2.93 MB

french, 2013

2

Des modÃ¨les animaux pour Ã©tudier lâorigine dÃ©veloppementale des maladies mÃ©taboliques de lâadulteÂ : application Ã lâÃ©tude du risque de diabÃ¨te

Portha, Bernard, Chavey, Audrey, Maulny, Linda, Gangnerau, Marie-NoÃ«lle, BailbÃ©, DaniÃ¨le, Dolz, Manuel, Jammes, HÃ©lÃ¨ne, Renard, Jean-Paul, Movassat, Jamileh

Journal:

Cahiers de Nutrition et de Diététique

Year:

2009

Language:

french

File:

PDF, 764 KB

french, 2009

3

Programmed disorders of β-cell development and function as one cause for type 2 diabetes? The GK rat paradigm

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

4

Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat

Gauguier, Dominique, Froguel, Philippe, Parent, Véronique, Bernard, Catherine, Bihoreau, Marie-Thérèse, Portha, Bernard, James, Michael R., Penicaud, Luc, Lathrop, Mark, Ktorza, Alain

Journal:

Nature Genetics

Year:

1996

File:

PDF, 593 KB

1996

5

Impaired Pancreatic Duct-cell Growth in Focal Areas of Regeneration After Partial Pancreatectomy in the Adult Goto-Kakizaki Rat, a Spontaneous Model of Non-insulin Dependent Diabetes Mellitus

Cedric Plachot, Bernard Portha

Journal:

Journal of Molecular Histology

Year:

2001

Language:

english

File:

PDF, 734 KB

english, 2001

6

Effect of benfluorex on insulin secretion and insulin action in streptozotocin-diabetic rats

Professor Bernard Portha, Patricia Serradas, Danielle Bailbé, Olivier Blondel, Françoise Picarel

Journal:

Diabetes/Metabolism Research and Reviews

Year:

1993

Language:

english

File:

PDF, 680 KB

english, 1993

7

Impaired β-cell regeneration after partial pancreatectomy in the adult Goto-Kakizaki rat, a spontaneous model of type

Cedric Plachot,Jamileh Movassat,Bernard Portha

Journal:

Histochemistry and Cell Biology

Year:

2001

Language:

english

File:

PDF, 224 KB

english, 2001

8

Hypothalamic serotonin–insulin signaling cross-talk and alterations in a type 2 diabetic model

Ioannis Papazoglou, Flavien Berthou, Nicolas Vicaire, Claude Rouch, Eirini M. Markaki, Danielle Bailbe, Bernard Portha, Mohammed Taouis, Kyriaki Gerozissis

Journal:

Molecular and Cellular Endocrinology

Year:

2012

Language:

english

File:

PDF, 507 KB

english, 2012

9

Effect of gliclazide treatment on insulin secretion and β-cell mass in non-insulin dependent diabetic Goto–Kakisaki rats

Nathalie Dachicourt, Danielle Bailbé, Marie-Noelle Gangnerau, Patricia Serradas, Denis Ravel, Bernard Portha

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 253 KB

english, 1998

10

Decreased ATP-Induced Synthesis and Ca2+-Stimulated Degradation of Polyphosphoinositides in Pancreatic Islets from Neonatally Streptozotocin-Diabetic Rats

Laurent Morin, Marie-Hélène Giroix, Bernard Portha

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 74 KB

english, 1996

11

Gαolf Identification by RT-PCR in Purified Normal Pancreatic B Cells and in Islets from Rat Models of Non-insulin-Dependent Diabetes

Stéphane Frayon, Marcia Pessah, Marie-Héléne Giroix, Dany Mercan, Claudine Boissard, Willy J. Malaisse, Bernard Portha, Jean-Michel Garel

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 243 KB

english, 1999

12

Metabolic and Secretory Response to d-Fructose in Pancreatic Islets from Adult Rats Injected with Streptozotocin during the Neonatal Period

Olivier Scruel, Marie-Hélène Giroix, Abdullah Sener, Bernard Portha, Willy J. Malaisse

Journal:

Molecular Genetics and Metabolism

Year:

1999

Language:

english

File:

PDF, 43 KB

english, 1999

13

Improvement in glucose-induced insulin secretion in diabetic rats after long-term gliclazide treatment: A comparative study using different models of non-insulin-dependent diabetes mellitus induced by neonatal streptozotocin

Bernard Portha, Patricia Serradas

Journal:

The American Journal of Medicine

Year:

1991

Language:

english

File:

PDF, 794 KB

english, 1991

14

d-Fenfluramine improves hepatic insulin action in streptozotocin-diabetic rats

Françoise Picarel-Blanchot, Danielle Bailbé, Bernard Portha

Journal:

European Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 522 KB

english, 1994

15

Neonatal streptozotocin injection: A model of glucotoxicity?

Willy J. Malaisse, Marie-Hélène Giroix, Dagmar Zähner, Greta Marynissen, Abdullah Sener, Bernard Portha

Journal:

Year:

1991

Language:

english

File:

PDF, 635 KB

english, 1991

16

Changes in insulin action and insulin secretion in the rat after dietary restriction early in life: Influence of dood restriction versus low-protein food restriction

Fraçoise Picarel-Blanchot, Carmen Alvarez, Danielle Bailbe, Ana-Maria Pascual-Leone, Bernard Portha

Journal:

Year:

1995

Language:

english

File:

PDF, 805 KB

english, 1995

17

Early reduction of circulating homocysteine levels in Goto–Kakizaki rat, a spontaneous nonobese model of type 2 diabetes

Christophe Noll, Gregory Lacraz, Jan Ehses, Josiane Coulaud, Danièle Bailbe, Jean-Louis Paul, Bernard Portha, Françoise Homo-Delarche, Nathalie Janel

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 364 KB

english, 2011

18

Comparison between d-[3-3H]- and d-[5-3H]glucose and fructose utilization in pancreatic islets from control and hereditarily diabetic rats

Marie-Hélène Giroix, Olivier Scruel, Philippe Courtois, Abdullah Sener, Bernard Portha, Willy J. Malaisse

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 178 KB

english, 2002

19

Insulin binding and insulin receptor tyrosine kinase activity are not altered in the liver of rats with non-insulin-dependent diabetes

Micheline Kergoat, Jean Simon, Bernard Portha

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 1.00 MB

english, 1988

20

Lack of deterioration of insulin action with aging in the GK rat: A contrasted adaptation as compared with nondiabetic rats

Cécile Berthelier, Micheline Kergoat, Bernard Portha

Journal:

Year:

1997

Language:

english

File:

PDF, 707 KB

english, 1997

21

Hippocampal neurovascular and hypothalamic–pituitary–adrenal axis alterations in spontaneously type 2 diabetic GK rats

Juan Beauquis, Françoise Homo-Delarche, Marie-Hélène Giroix, Jan Ehses, Josiane Coulaud, Paulina Roig, Bernard Portha, Alejandro F. De Nicola, Flavia Saravia

Journal:

Experimental Neurology

Year:

2010

Language:

english

File:

PDF, 1.53 MB

english, 2010

22

Effect of diet on glucose tolerance and insulin response in chemically diabetic rats

Bernard Portha, Marie-Hélène Giroix, Luc Picon

Journal:

Year:

1982

Language:

english

File:

PDF, 636 KB

english, 1982

23

Effect of exogenous insulin on glucose kinetics in rats with noninsulin-dependent diabetes

Micheline Kergoat, Bernard Portha, Luc Picon

Journal:

Year:

1985

Language:

english

File:

PDF, 712 KB

english, 1985

24

Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival

Julien Véret, Nicolas Coant, Irina A. Gorshkova, Paola Giussani, Magali Fradet, Elena Riccitelli, Anastasia Skobeleva, Jonathan Goya, Nadim Kassis, Viswanathan Natarajan, Bernard Portha, Evgeny V. Ber

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

25

Models for pharmacological activation of beta-cell regeneration in diabetes

Jamileh Movassat, Bernard Portha

Journal:

Drug Discovery Today: Disease Models

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

26

Localization of Vasoactive Intestinal Peptide Binding Sites in Rat Pancreatic Islets by Computer-Assisted Analysis of Electron Microscopy Video-Autoradiographs

ANNY ANTEUNIS, ANY ASTESANO, GILLES HEJBLUM, JEAN-CLAUDE MARIE, BERNARD PORTHA, GABRIEL ROSSELIN

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 85 KB

english, 1988

27

A Computer-Assisted Analysis of Ultrastructural Autoradiographs Applied to the Localization of Vasoactive Intestinal Peptide Binding Sites in Pancreatic Acini

GILLES HEJBLUM, ANNY ANTEUNIS, ANY ASTESANO, JEAN-CLAUDE MARIE, BERNARD PORTHA, GABRIEL ROSSELIN

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 85 KB

english, 1988

28

Procyanidins Modulate MicroRNA Expression in Pancreatic Islets

Castell-Auví, Anna, Cedó, Lídia, Movassat, Jamileh, Portha, Bernard, Sánchez-Cabo, Fátima, Pallarès, Victor, Blay, Mayte, Pinent, Montserrat, Ardévol, Anna

Journal:

Journal of Agricultural and Food Chemistry

Year:

2013

Language:

english

File:

PDF, 2.25 MB

english, 2013

29

PARIS.

Tourrel, Cécile, Bailbe, Danielle, Kergoat, Micheline, Portha, Bernard

Journal:

Year:

1906

Language:

english

File:

PDF, 397 KB

english, 1906

30

Glucagon like-peptide 1 or exendin-4 administration limited to the transient neonatal hyperglycemic period in the n0-STZ rat model of NIDDM exerts a long-term favorable influence on glycemic control in the adult

Tourrel, Cécile, Bailbe, Danielle, Kergoat, Micheline, Portha, Bernard

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

31

P153 L’insulino-résistance n’est pas associée à une altération de la fonction mitochondriale dans le muscle squelettique des rats diabétiques Goto-Kakizaki : une étude in vivo.

Macia, M., Pecchi, E., Vilmen, C., Desrois, M., Portha, B., Bernard, M., Bendahan, D., Giannesini, B.

Journal:

Diabetes & Metabolism

Year:

2014

Language:

french

File:

PDF, 52 KB

french, 2014

32

Structural requirements for gastric inhibitory polypeptide (GIP) receptor binding and stimulation of insulin release

Maletti, Maura, Carlquist, Mats, Portha, Bernard, Kergoat, Micheline, Mutt, Viktor, Rosselin, Gabriel

Journal:

Year:

1986

Language:

english

File:

PDF, 325 KB

english, 1986

33

Decreased glucagon-stimulated cyclic AMP production by isolated liver cells of rats with type 2 diabetes

Portha, Bernard, Chamras, Hilda, Broer, Yvonne, Picon, Luc, Rosselin, Gabriel

Journal:

Molecular and Cellular Endocrinology

Year:

1983

Language:

english

File:

PDF, 1008 KB

english, 1983

34

Defective functional β-cell mass and Type 2 diabetes in the Goto–Kakizaki rat model

Portha, Bernard, Lacraz, G, Dolz, M, Homo-Delarche, F, Giroix, M-H, Movassat, J

Journal:

Expert Review of Endocrinology & Metabolism

Year:

2007

Language:

english

File:

PDF, 1.23 MB

english, 2007

35

Pancreatic beta-cell regeneration after 48-h glucose infusion in mildly diabetic rats is not correlated with functional improvement

Bernard, C., Thibault, C., Berthault, M. F., Magnan, C., Saulnier, C., Portha, B., Pralong, W. F., Penicaud, L., Ktorza, A.

Journal:

Year:

1998

Language:

english

File:

PDF, 496 KB

english, 1998

36

Early-Life Origins of Type 2 Diabetes: Fetal Programming of the Beta-Cell Mass

Portha, Bernard, Chavey, Audrey, Movassat, Jamileh

Journal:

Experimental Diabetes Research

Year:

2011

Language:

english

File:

PDF, 358 KB

english, 2011

37

Activation of the GLP-1 Receptor Signalling Pathway: A Relevant Strategy to Repair a Deficient Beta-Cell Mass

Portha, Bernard, Tourrel-Cuzin, Cécile, Movassat, Jamileh

Journal:

Experimental Diabetes Research

Year:

2011

Language:

english

File:

PDF, 613 KB

english, 2011

38

Animal Models of Diabetes and Its Associated Complications

Islam, Md. Shahidul, Koya, Daisuke, Portha, Bernard

Journal:

Journal of Diabetes Research

Year:

2013

Language:

english

File:

PDF, 40 KB

english, 2013

39

The Novel Oral Drug Subetta Exerts an Antidiabetic Effect in the Diabetic Goto-Kakizaki Rat: Comparison with Rosiglitazone

Bailbé, Danielle, Philippe, Erwann, Gorbunov, Evgeniy, Tarasov, Sergey, Epstein, Oleg, Portha, Bernard

Journal:

Journal of Diabetes Research

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

40

Upregulation of eNOS and unchanged energy metabolism in increased susceptibility of the aging type 2 diabetic GK rat heart to ischemic injury

Desrois, M., Clarke, K., Lan, C., Dalmasso, C., Cole, M., Portha, B., Cozzone, P. J., Bernard, M.

Journal:

AJP Heart and Circulatory Physiology

Year:

2010

Language:

english

File:

PDF, 606 KB

english, 2010

41

0061 : Exercice training impaired energy metabolism and function of the type 2 diabetic Goto-Kakizaki (GK) rat heart during ischaemiareperfusion injury

Desrois, Martine, Lan, Carole, Macia, Michael, Portha, Bernard, Bailbé, Danielle, Giannesini, Benoit, Bendahan, David, Movassat, Jamileh, Cozzone, Patrick J., Bernard, Monique

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

42

Local In Vivo GSK3β Knockdown Promotes Pancreatic β Cell and Acinar Cell Regeneration in 90% Pancreatectomized Rat

Figeac, Florence, Ilias, Anissa, Bailbe, Danielle, Portha, Bernard, Movassat, Jamileh

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

43

Metabolic and Secretory Interactions between d -Glucose and d -Fructose in Islets from GK Rats 1

Giroix, Marie-Helene, Scruel, Olivier, Ladriere, Laurence, Sener, Abdullah, Portha, Bernard, Malaisse, Willy J.

Journal:

Year:

1999

Language:

english

File:

PDF, 194 KB

english, 1999

44

Altered Activity of the Autonomous Nervous System as a Determinant of the Impaired β-Cell Secretory Response after Protein-Energy Restriction in the Rat 1

Leon-Quinto, Trinidad, Magnan, Christophe, Portha, Bernard

Journal:

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

45

Protein-Caloric Food Restriction Affects Insulin-Like Growth Factor System in Fetal Wistar Rat

Martín, M. A, Serradas, P., Ramos, S., Fernández, E., Goya, L., Gangnerau, M. N., Lacorne, M., Pascual-Leone, A. M., Escrivá, F., Portha, Bernard, Álvarez, C.

Journal:

Year:

2005

Language:

english

File:

PDF, 203 KB

english, 2005

46

Undernutrition of the GK rat during gestation improves pancreatic IGF-2 and beta-cell mass in the fetuses

Fernández-Millán, Elisa, Gangnerau, Marie Noëlle, De Miguel-Santos, Laura, Calderari, Sophie, Serradas, Patricia, Escrivá, Fernando, Portha, Bernard, Álvarez, Carmen

Journal:

Year:

2009

Language:

english

File:

PDF, 626 KB

english, 2009

47

Increased Insulin Action in Cultured Hepatocytes from Rats with Diabetes Induced by Neonatal Streptozotocin*

MELIN, BRIGITTE, CARON, MARTINE, CHERQUI, GISÉLE, BLIVET, MARIE-JOSE, BAILBE, DANIELLE, PICARD, JACQUES, CAPEAU, JACQUELINE, PORTHA, BERNARD

Journal:

Year:

1991

Language:

english

File:

PDF, 1.24 MB

english, 1991

48

The Desensitization of Normal B-Cells to Glucose in vitro Is Transient and not Related to High Glucose Levels*

GIROIX, MARIE-HÉLÉNE, SERRADAS, PATRICIA, PORTHA, BERNARD

Journal:

Year:

1989

Language:

english

File:

PDF, 1.10 MB

english, 1989

49

Postmaturity in the Rat: Glucose Metabolism in the Fetus and the Neonate

Provost, Evelyne Le, Portha, Bernard, Cros, Jean-Claudu, Picon, Luc

Journal:

Pediatric Research

Year:

1980

Language:

english

File:

PDF, 561 KB

english, 1980

50

Streptozotocin Treatment at Birth Induces a Parallel Depletion of Thyrotropin-Releasing Hormone and Insulin in the Rat Pancreas during Development

ARATAN-SPIRE, SONIA, WOLF, BRYAN, PORTHA, BERNARD, BAILBE, DANIELLE, CZERNICHOW, PAUL

Journal:

Year:

1984

Language:

english

File:

PDF, 437 KB

english, 1984

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